It is Mr Ghani's first visit to Pakistan since taking office in September
Afghan President Ashraf
Ghani is to meet Pakistani leaders on his first visit to Islamabad - a
trip being seen as a chance to reset troubled ties.
It is Mr Ghani's first visit to Pakistan since taking office in September. His predecessor, Hamid Karzai, routinely criticised Pakistan for sheltering militant groups.
Pakistan always rejected such complaints and accused Afghanistan of failing to stop cross-border attacks.
Officials on both sides hope this visit will provide a fresh start in the context of such troubled relations.
In the run-up to the visit, Pakistan's powerful army chief Raheel Sharif, and later the new chief of the country's main intelligence agency the ISI, have held talks in Kabul.
Pakistan says its current military offensive in the tribal region of North Waziristan is an evidence of its commitment to destroy militant safe havens.
Its foreign ministry spokeswoman Tasnim Aslam said that during Mr Ghani's visit the two sides would discuss improving economic ties, border security and counter-terrorism.
"Peace and stability in Afghanistan are in Pakistan's vital interest," Mr Aslam is quoted as saying by the AP news agency.
While Islamabad insists it wants to see a stable and peaceful Afghanistan, it remains wary of its traditional rival, India, expanding its influence along the border in Afghanistan, the BBC's Shahzeb Jillani in Karachi points out.